80 Results for "

Hypoxis angustifolia Lam.

" in MedChemExpress (MCE) Product Catalog:
Products (80)

80 Results for "Hypoxis angustifolia Lam." in MCE Product Catalog:

44
44 Publications Verification
Cat. No.: HY-14644
CAS No.: 541550-19-0
Purity:  99.80%
Synonyms: STA 5326; LAM-002A free base; AIT-101
Research Areas:  

Inflammation/Immunology Cancer

Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
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44
44 Publications Verification
Cat. No.: HY-14644A
CAS No.: 870087-36-8
Purity:  99.83%
Synonyms: STA 5326 mesylate; LAM-002A; AIT-101 mesylate
Research Areas:  

Inflammation/Immunology Cancer

Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
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6
6 Cited Publications
Cat. No.: HY-N0365
CAS No.: 81-27-6
Sennoside A is an anthraquinone glycoside found in senna (Cassia angustifolia). Sennoside A is an HIV-1 inhibitor (IC50=3.8 μM) that inhibits HIV-1 replication. Sennoside A also inhibits HIV-1 reverse transcriptase (RT)-related DNA polymerase (RDDP) and ribonuclease H (Ribonuclease H) with IC50s of 1.9 μM and 5.3 μM, respectively .
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4
4 Cited Publications
Cat. No.: HY-N0778
CAS No.: 55033-90-4
Isorhamnetin-3-O-neohespeidoside is a flavonoid. Isorhamnetin-3-O-neohespeidoside can be isolated from Typha angustifolia. Isorhamnetin-3-O-neohespeidoside inhibits xanthine oxidase activity with an IC50 of 48.75 μg mL. Isorhamnetin-3-O-neohespeidoside has antioxidant and osteoclastogenic activities. Isorhamnetin-3-O-neohespeidoside can be used in research of bone .
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1
1 Cited Publications
Cat. No.: HY-117419A
CAS No.: 25905-14-0
Purity:  ≥98.0%
(±)-Lavandulyl acetate can be isolated from the oil components of Lavandula angustifolia Mill .
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Cat. No.: HY-129467
CAS No.: 56472-29-8
Purity:  ≥98.0%
Synonyms: 2-Hydroxyoleic acid; 2-OHOA; LAM561
Target:  

Apoptosis

Research Areas:  

Cancer

(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a synthetic oleic acid (OA) derivative that binds to the plasma membrane and alters lipid organization. (Rac)-Idroxioleic acid has anti-tumor effect .
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Cat. No.: HY-150229
CAS No.: 2803699-70-7
Purity:  98.84%
306-N16B is a selective lung-targeted lipid nanoparticle that reversibly targets lung endothelial cells and specific immune cells through selective adsorption of a protein corona mediated by differences in tail structure (such as fibrinogen β/γ chain). 306-N16B binds to specific plasma proteins in the blood to form a protein corona, which guides the particles to be enriched in the lungs, releases mRNA and promotes target cell gene expression, exerts efficient lung cell transfection activity, and can precisely regulate gene delivery of different cell types in the lungs (such as endothelial cells and macrophages). 306-N16B can be used in gene therapy technologies for hereditary lung diseases including pulmonary lymphangioleiomyomatosis (LAM), restoring tumor suppressor function by delivering Tsc2 mRNA, and can also be used for lung-specific mRNA vaccines and gene editing therapies .
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Cat. No.: HY-N1973
CAS No.: 37271-17-3
Sennoside D is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia) .
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Cat. No.: HY-N6935
CAS No.: 517-44-2
Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation .
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Cat. No.: HY-N12281
CAS No.: 517-43-1
Sennoside is an orally active apoptosis inducer and stimulant laxative, found in Senna (Cassia angustifolia). Sennoside induces overexpression of wild-type p53 and p21/WAF as part of pathways mediating colonic epithelial cell apoptosis. Sennoside stimulates colonic peristalsis, reverses net water, sodium, chloride absorption to secretion and enhances potassium and calcium secretion. Sennoside increases paracellular permeability to small molecules, accelerates colon transit and softens fecal pellets. Sennoside can be used for the research of constipation, melanosis coli, and colorectal cancer .
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Cat. No.: HY-N8503
CAS No.: 147821-49-6
Niazimicin can be isolated from seeds and leaves of Moringa oleifera Lam. Niazimicin is thiocarbamate compound .
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Cat. No.: HY-N0365R
CAS No.: 81-27-6
Sennoside A (Standard) is the analytical standard of Sennoside A. This product is intended for research and analytical applications. Sennoside A is an anthraquinone glycoside, found in Senna (Cassia angustifolia) . Sennoside A is a HIV-1 inhibitor effective on HIV-1 replication .
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Cat. No.: HY-W555382
CAS No.: 55396-45-7
Synonyms: 2-Nonylquinolin-4(1H)-one
Pseudane IX, a compound isolated from the leaves of Ruta angustifolia, has strong anti-HCV activity with an IC50 value of 1.4 μg/mL. Pseudane IX reduces HCV RNA replication and viral protein synthesis levels .
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Cat. No.: HY-N10842
CAS No.: 88140-31-2
6-Formyllimetin is a natural product isolated from the root bark of T. asiatica LAM .
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Cat. No.: HY-N10641
CAS No.: 27548-88-5
Epinodosinol is a diterpenoid derived from plant Rabdosia angustifolia. Epinodosinol has inhibitory activity against certain cancer cells .
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Cat. No.: HY-117419
CAS No.: 20777-39-3
(-)-Lavandulyl acetate is a nature product that can be found in Lavandula angustifolia. (-)-Lavandulyl acetate shows toxicity for mosquito vectors. (-)-Lavandulyl acetate can be used as mosquito larvicide .
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Cat. No.: HY-N10803
CAS No.: 15575-50-5
(+)-6-(3-Chloro-2-hydroxy-3-methylbutyl)-5,7-dimethoxycoumarin is a nature product that could be isolated form the root bark of Toddalia asiatica (L.) LAM .
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Cat. No.: HY-164915
CAS No.: 1218932-97-8
Target:  

Bacterial

Research Areas:  

Metabolic Disease

5-InoAz is an inositol analogue used as a metabolic probe for labeling the mycobacterial cell envelope. 5-InoAz integrates into cell envelope glycolipids [phosphatidylinositol mannoside (PIM), PIM-anchored lipomannan (LM), and lipoarabinomannan (LAM)] .
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Cat. No.: HY-N0366R
CAS No.: 128-57-4
Sennoside B (Standard) is the analytical standard of Sennoside B. This product is intended for research and analytical applications. Sennoside B is an anthraquinone glycoside, found in large quantities in leaves and pods of Senna (Cassia angustifolia) . Sennoside B can inhibit PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway .
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Cat. No.: HY-N9097
CAS No.: 122001-32-5
Niazirin is an orally active antioxidant. Niazirin can be isolated from Moringa oleifera Lam. Niazirin reduces the production levels of ROS and MDA, while increasing the levels of superoxide dismutase SOD and glutathione peroxidase GPx. Niazirin also abolishes high glucose-induced PKCζ activation and inhibits Nox4 protein expression. Niazirin exhibits excellent free radical scavenging activity. Niazirin significantly inhibits high glucose-induced proliferation of vascular smooth muscle cells. Niazirin can be used in the research of diabetic atherosclerosis .
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